turnkey langendorff perfusion systems Search Results


langendorff perfusion system  (POWERLAB INC)
90
POWERLAB INC langendorff perfusion system
Langendorff Perfusion System, supplied by POWERLAB INC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/langendorff perfusion system/product/POWERLAB INC
Average 90 stars, based on 1 article reviews
langendorff perfusion system - by Bioz Stars, 2026-04
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langendorff perfusion system  (Zhongshi Duqing Biotech Co Ltd)
90
Zhongshi Duqing Biotech Co Ltd langendorff perfusion system
Langendorff Perfusion System, supplied by Zhongshi Duqing Biotech Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/langendorff perfusion system/product/Zhongshi Duqing Biotech Co Ltd
Average 90 stars, based on 1 article reviews
langendorff perfusion system - by Bioz Stars, 2026-04
90/100 stars
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langendorff perfusion system  (Radnoti LLC)
90
Radnoti LLC langendorff perfusion system
( A and B ) RBOES was interfaced to the cadaver heart tissue (A) and the potential response under the light stimulation (1 Hz, 100 ms) (B). ( C and D ) RBOES was interfaced to an intercostal nerve (C) and the potential response under the light stimulation (0.5 Hz, 100 ms) (D). The rubbery semiconducting nanofilm side was directly placed on the tissues to form the interface. The potential signals were extracted using a pair of clamp recording electrodes. ( E ) Schematic of the measurement setup including a <t>Langendorff</t> system that maintained the rat hearts. An adult rat heart was placed in an incubator (37°C and 5% CO 2 ), and oxygenated Krebs-Henseleit buffer reservoir was perfused into the aorta of the heart. A 530-nm LED light was focused through an amplifying lens on the RBOES placed onto the exposed myocardium on the right atrium. ECG electrodes were sutured on the heart to record the signals with a data acquisition system. ( F ) Optical images of the perfused rat heart with the RBOES (marked in the dotted square) and the ECG electrodes. ( G ) Real-time beating rate of the perfused rat heart under consecutive stimulation with targeted beating rates of 120 and 150 bpm (marked in the dotted black line). ( H ) ECG signals of the perfused rat heart under optoelectronic stimulation. The top row shows the ECG signals obtained from prestimulation (0 to 5 s), during stimulation (680 to 685 s), and post-stimulation (771 to 776 s) of 2-Hz light illumination. The bottom row shows ECG signals of the perfused rat heart obtained from prestimulation (600 to 605 s), during stimulation (2240 to 2245 s), and post-stimulation (2262 to 2267 s) of 2.5-Hz light illumination. ( I ) Typical ECG with PQRST waves was observed in the signal during stimulation in (H).
Langendorff Perfusion System, supplied by Radnoti LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/langendorff perfusion system/product/Radnoti LLC
Average 90 stars, based on 1 article reviews
langendorff perfusion system - by Bioz Stars, 2026-04
90/100 stars
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langendorff perfusion cell isolation system ac-7034  (Cellutron Inc)
90
Cellutron Inc langendorff perfusion cell isolation system ac-7034
( A and B ) RBOES was interfaced to the cadaver heart tissue (A) and the potential response under the light stimulation (1 Hz, 100 ms) (B). ( C and D ) RBOES was interfaced to an intercostal nerve (C) and the potential response under the light stimulation (0.5 Hz, 100 ms) (D). The rubbery semiconducting nanofilm side was directly placed on the tissues to form the interface. The potential signals were extracted using a pair of clamp recording electrodes. ( E ) Schematic of the measurement setup including a <t>Langendorff</t> system that maintained the rat hearts. An adult rat heart was placed in an incubator (37°C and 5% CO 2 ), and oxygenated Krebs-Henseleit buffer reservoir was perfused into the aorta of the heart. A 530-nm LED light was focused through an amplifying lens on the RBOES placed onto the exposed myocardium on the right atrium. ECG electrodes were sutured on the heart to record the signals with a data acquisition system. ( F ) Optical images of the perfused rat heart with the RBOES (marked in the dotted square) and the ECG electrodes. ( G ) Real-time beating rate of the perfused rat heart under consecutive stimulation with targeted beating rates of 120 and 150 bpm (marked in the dotted black line). ( H ) ECG signals of the perfused rat heart under optoelectronic stimulation. The top row shows the ECG signals obtained from prestimulation (0 to 5 s), during stimulation (680 to 685 s), and post-stimulation (771 to 776 s) of 2-Hz light illumination. The bottom row shows ECG signals of the perfused rat heart obtained from prestimulation (600 to 605 s), during stimulation (2240 to 2245 s), and post-stimulation (2262 to 2267 s) of 2.5-Hz light illumination. ( I ) Typical ECG with PQRST waves was observed in the signal during stimulation in (H).
Langendorff Perfusion Cell Isolation System Ac 7034, supplied by Cellutron Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/langendorff perfusion cell isolation system ac-7034/product/Cellutron Inc
Average 90 stars, based on 1 article reviews
langendorff perfusion cell isolation system ac-7034 - by Bioz Stars, 2026-04
90/100 stars
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hugo sachs elektronik langendorff perfusion system  (Harvard Bioscience)
90
Harvard Bioscience hugo sachs elektronik langendorff perfusion system
( A and B ) RBOES was interfaced to the cadaver heart tissue (A) and the potential response under the light stimulation (1 Hz, 100 ms) (B). ( C and D ) RBOES was interfaced to an intercostal nerve (C) and the potential response under the light stimulation (0.5 Hz, 100 ms) (D). The rubbery semiconducting nanofilm side was directly placed on the tissues to form the interface. The potential signals were extracted using a pair of clamp recording electrodes. ( E ) Schematic of the measurement setup including a <t>Langendorff</t> system that maintained the rat hearts. An adult rat heart was placed in an incubator (37°C and 5% CO 2 ), and oxygenated Krebs-Henseleit buffer reservoir was perfused into the aorta of the heart. A 530-nm LED light was focused through an amplifying lens on the RBOES placed onto the exposed myocardium on the right atrium. ECG electrodes were sutured on the heart to record the signals with a data acquisition system. ( F ) Optical images of the perfused rat heart with the RBOES (marked in the dotted square) and the ECG electrodes. ( G ) Real-time beating rate of the perfused rat heart under consecutive stimulation with targeted beating rates of 120 and 150 bpm (marked in the dotted black line). ( H ) ECG signals of the perfused rat heart under optoelectronic stimulation. The top row shows the ECG signals obtained from prestimulation (0 to 5 s), during stimulation (680 to 685 s), and post-stimulation (771 to 776 s) of 2-Hz light illumination. The bottom row shows ECG signals of the perfused rat heart obtained from prestimulation (600 to 605 s), during stimulation (2240 to 2245 s), and post-stimulation (2262 to 2267 s) of 2.5-Hz light illumination. ( I ) Typical ECG with PQRST waves was observed in the signal during stimulation in (H).
Hugo Sachs Elektronik Langendorff Perfusion System, supplied by Harvard Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/hugo sachs elektronik langendorff perfusion system/product/Harvard Bioscience
Average 90 stars, based on 1 article reviews
hugo sachs elektronik langendorff perfusion system - by Bioz Stars, 2026-04
90/100 stars
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langendorff extracorporeal perfusion system  (Zhongshi Duqing Biotech Co Ltd)
90
Zhongshi Duqing Biotech Co Ltd langendorff extracorporeal perfusion system
( A and B ) RBOES was interfaced to the cadaver heart tissue (A) and the potential response under the light stimulation (1 Hz, 100 ms) (B). ( C and D ) RBOES was interfaced to an intercostal nerve (C) and the potential response under the light stimulation (0.5 Hz, 100 ms) (D). The rubbery semiconducting nanofilm side was directly placed on the tissues to form the interface. The potential signals were extracted using a pair of clamp recording electrodes. ( E ) Schematic of the measurement setup including a <t>Langendorff</t> system that maintained the rat hearts. An adult rat heart was placed in an incubator (37°C and 5% CO 2 ), and oxygenated Krebs-Henseleit buffer reservoir was perfused into the aorta of the heart. A 530-nm LED light was focused through an amplifying lens on the RBOES placed onto the exposed myocardium on the right atrium. ECG electrodes were sutured on the heart to record the signals with a data acquisition system. ( F ) Optical images of the perfused rat heart with the RBOES (marked in the dotted square) and the ECG electrodes. ( G ) Real-time beating rate of the perfused rat heart under consecutive stimulation with targeted beating rates of 120 and 150 bpm (marked in the dotted black line). ( H ) ECG signals of the perfused rat heart under optoelectronic stimulation. The top row shows the ECG signals obtained from prestimulation (0 to 5 s), during stimulation (680 to 685 s), and post-stimulation (771 to 776 s) of 2-Hz light illumination. The bottom row shows ECG signals of the perfused rat heart obtained from prestimulation (600 to 605 s), during stimulation (2240 to 2245 s), and post-stimulation (2262 to 2267 s) of 2.5-Hz light illumination. ( I ) Typical ECG with PQRST waves was observed in the signal during stimulation in (H).
Langendorff Extracorporeal Perfusion System, supplied by Zhongshi Duqing Biotech Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/langendorff extracorporeal perfusion system/product/Zhongshi Duqing Biotech Co Ltd
Average 90 stars, based on 1 article reviews
langendorff extracorporeal perfusion system - by Bioz Stars, 2026-04
90/100 stars
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langendorff heart perfusion system for rodents  (Radnoti LLC)
90
Radnoti LLC langendorff heart perfusion system for rodents
( A and B ) RBOES was interfaced to the cadaver heart tissue (A) and the potential response under the light stimulation (1 Hz, 100 ms) (B). ( C and D ) RBOES was interfaced to an intercostal nerve (C) and the potential response under the light stimulation (0.5 Hz, 100 ms) (D). The rubbery semiconducting nanofilm side was directly placed on the tissues to form the interface. The potential signals were extracted using a pair of clamp recording electrodes. ( E ) Schematic of the measurement setup including a <t>Langendorff</t> system that maintained the rat hearts. An adult rat heart was placed in an incubator (37°C and 5% CO 2 ), and oxygenated Krebs-Henseleit buffer reservoir was perfused into the aorta of the heart. A 530-nm LED light was focused through an amplifying lens on the RBOES placed onto the exposed myocardium on the right atrium. ECG electrodes were sutured on the heart to record the signals with a data acquisition system. ( F ) Optical images of the perfused rat heart with the RBOES (marked in the dotted square) and the ECG electrodes. ( G ) Real-time beating rate of the perfused rat heart under consecutive stimulation with targeted beating rates of 120 and 150 bpm (marked in the dotted black line). ( H ) ECG signals of the perfused rat heart under optoelectronic stimulation. The top row shows the ECG signals obtained from prestimulation (0 to 5 s), during stimulation (680 to 685 s), and post-stimulation (771 to 776 s) of 2-Hz light illumination. The bottom row shows ECG signals of the perfused rat heart obtained from prestimulation (600 to 605 s), during stimulation (2240 to 2245 s), and post-stimulation (2262 to 2267 s) of 2.5-Hz light illumination. ( I ) Typical ECG with PQRST waves was observed in the signal during stimulation in (H).
Langendorff Heart Perfusion System For Rodents, supplied by Radnoti LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/langendorff heart perfusion system for rodents/product/Radnoti LLC
Average 90 stars, based on 1 article reviews
langendorff heart perfusion system for rodents - by Bioz Stars, 2026-04
90/100 stars
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langendorff perfusion system for isolated mouse hearts  (Radnoti LLC)
90
Radnoti LLC langendorff perfusion system for isolated mouse hearts
( A and B ) RBOES was interfaced to the cadaver heart tissue (A) and the potential response under the light stimulation (1 Hz, 100 ms) (B). ( C and D ) RBOES was interfaced to an intercostal nerve (C) and the potential response under the light stimulation (0.5 Hz, 100 ms) (D). The rubbery semiconducting nanofilm side was directly placed on the tissues to form the interface. The potential signals were extracted using a pair of clamp recording electrodes. ( E ) Schematic of the measurement setup including a <t>Langendorff</t> system that maintained the rat hearts. An adult rat heart was placed in an incubator (37°C and 5% CO 2 ), and oxygenated Krebs-Henseleit buffer reservoir was perfused into the aorta of the heart. A 530-nm LED light was focused through an amplifying lens on the RBOES placed onto the exposed myocardium on the right atrium. ECG electrodes were sutured on the heart to record the signals with a data acquisition system. ( F ) Optical images of the perfused rat heart with the RBOES (marked in the dotted square) and the ECG electrodes. ( G ) Real-time beating rate of the perfused rat heart under consecutive stimulation with targeted beating rates of 120 and 150 bpm (marked in the dotted black line). ( H ) ECG signals of the perfused rat heart under optoelectronic stimulation. The top row shows the ECG signals obtained from prestimulation (0 to 5 s), during stimulation (680 to 685 s), and post-stimulation (771 to 776 s) of 2-Hz light illumination. The bottom row shows ECG signals of the perfused rat heart obtained from prestimulation (600 to 605 s), during stimulation (2240 to 2245 s), and post-stimulation (2262 to 2267 s) of 2.5-Hz light illumination. ( I ) Typical ECG with PQRST waves was observed in the signal during stimulation in (H).
Langendorff Perfusion System For Isolated Mouse Hearts, supplied by Radnoti LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/langendorff perfusion system for isolated mouse hearts/product/Radnoti LLC
Average 90 stars, based on 1 article reviews
langendorff perfusion system for isolated mouse hearts - by Bioz Stars, 2026-04
90/100 stars
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langendorff perfusion system radnoti 120103ez  (Radnoti LLC)
90
Radnoti LLC langendorff perfusion system radnoti 120103ez
( A and B ) RBOES was interfaced to the cadaver heart tissue (A) and the potential response under the light stimulation (1 Hz, 100 ms) (B). ( C and D ) RBOES was interfaced to an intercostal nerve (C) and the potential response under the light stimulation (0.5 Hz, 100 ms) (D). The rubbery semiconducting nanofilm side was directly placed on the tissues to form the interface. The potential signals were extracted using a pair of clamp recording electrodes. ( E ) Schematic of the measurement setup including a <t>Langendorff</t> system that maintained the rat hearts. An adult rat heart was placed in an incubator (37°C and 5% CO 2 ), and oxygenated Krebs-Henseleit buffer reservoir was perfused into the aorta of the heart. A 530-nm LED light was focused through an amplifying lens on the RBOES placed onto the exposed myocardium on the right atrium. ECG electrodes were sutured on the heart to record the signals with a data acquisition system. ( F ) Optical images of the perfused rat heart with the RBOES (marked in the dotted square) and the ECG electrodes. ( G ) Real-time beating rate of the perfused rat heart under consecutive stimulation with targeted beating rates of 120 and 150 bpm (marked in the dotted black line). ( H ) ECG signals of the perfused rat heart under optoelectronic stimulation. The top row shows the ECG signals obtained from prestimulation (0 to 5 s), during stimulation (680 to 685 s), and post-stimulation (771 to 776 s) of 2-Hz light illumination. The bottom row shows ECG signals of the perfused rat heart obtained from prestimulation (600 to 605 s), during stimulation (2240 to 2245 s), and post-stimulation (2262 to 2267 s) of 2.5-Hz light illumination. ( I ) Typical ECG with PQRST waves was observed in the signal during stimulation in (H).
Langendorff Perfusion System Radnoti 120103ez, supplied by Radnoti LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/langendorff perfusion system radnoti 120103ez/product/Radnoti LLC
Average 90 stars, based on 1 article reviews
langendorff perfusion system radnoti 120103ez - by Bioz Stars, 2026-04
90/100 stars
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adapted rabbit heart langendorff perfusion system radnoti lc  (Radnoti LLC)
90
Radnoti LLC adapted rabbit heart langendorff perfusion system radnoti lc
( A and B ) RBOES was interfaced to the cadaver heart tissue (A) and the potential response under the light stimulation (1 Hz, 100 ms) (B). ( C and D ) RBOES was interfaced to an intercostal nerve (C) and the potential response under the light stimulation (0.5 Hz, 100 ms) (D). The rubbery semiconducting nanofilm side was directly placed on the tissues to form the interface. The potential signals were extracted using a pair of clamp recording electrodes. ( E ) Schematic of the measurement setup including a <t>Langendorff</t> system that maintained the rat hearts. An adult rat heart was placed in an incubator (37°C and 5% CO 2 ), and oxygenated Krebs-Henseleit buffer reservoir was perfused into the aorta of the heart. A 530-nm LED light was focused through an amplifying lens on the RBOES placed onto the exposed myocardium on the right atrium. ECG electrodes were sutured on the heart to record the signals with a data acquisition system. ( F ) Optical images of the perfused rat heart with the RBOES (marked in the dotted square) and the ECG electrodes. ( G ) Real-time beating rate of the perfused rat heart under consecutive stimulation with targeted beating rates of 120 and 150 bpm (marked in the dotted black line). ( H ) ECG signals of the perfused rat heart under optoelectronic stimulation. The top row shows the ECG signals obtained from prestimulation (0 to 5 s), during stimulation (680 to 685 s), and post-stimulation (771 to 776 s) of 2-Hz light illumination. The bottom row shows ECG signals of the perfused rat heart obtained from prestimulation (600 to 605 s), during stimulation (2240 to 2245 s), and post-stimulation (2262 to 2267 s) of 2.5-Hz light illumination. ( I ) Typical ECG with PQRST waves was observed in the signal during stimulation in (H).
Adapted Rabbit Heart Langendorff Perfusion System Radnoti Lc, supplied by Radnoti LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/adapted rabbit heart langendorff perfusion system radnoti lc/product/Radnoti LLC
Average 90 stars, based on 1 article reviews
adapted rabbit heart langendorff perfusion system radnoti lc - by Bioz Stars, 2026-04
90/100 stars
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langendorff perfusion system isolated heart system  (emka TECHNOLOGIES S A S)
90
emka TECHNOLOGIES S A S langendorff perfusion system isolated heart system
( A and B ) RBOES was interfaced to the cadaver heart tissue (A) and the potential response under the light stimulation (1 Hz, 100 ms) (B). ( C and D ) RBOES was interfaced to an intercostal nerve (C) and the potential response under the light stimulation (0.5 Hz, 100 ms) (D). The rubbery semiconducting nanofilm side was directly placed on the tissues to form the interface. The potential signals were extracted using a pair of clamp recording electrodes. ( E ) Schematic of the measurement setup including a <t>Langendorff</t> system that maintained the rat hearts. An adult rat heart was placed in an incubator (37°C and 5% CO 2 ), and oxygenated Krebs-Henseleit buffer reservoir was perfused into the aorta of the heart. A 530-nm LED light was focused through an amplifying lens on the RBOES placed onto the exposed myocardium on the right atrium. ECG electrodes were sutured on the heart to record the signals with a data acquisition system. ( F ) Optical images of the perfused rat heart with the RBOES (marked in the dotted square) and the ECG electrodes. ( G ) Real-time beating rate of the perfused rat heart under consecutive stimulation with targeted beating rates of 120 and 150 bpm (marked in the dotted black line). ( H ) ECG signals of the perfused rat heart under optoelectronic stimulation. The top row shows the ECG signals obtained from prestimulation (0 to 5 s), during stimulation (680 to 685 s), and post-stimulation (771 to 776 s) of 2-Hz light illumination. The bottom row shows ECG signals of the perfused rat heart obtained from prestimulation (600 to 605 s), during stimulation (2240 to 2245 s), and post-stimulation (2262 to 2267 s) of 2.5-Hz light illumination. ( I ) Typical ECG with PQRST waves was observed in the signal during stimulation in (H).
Langendorff Perfusion System Isolated Heart System, supplied by emka TECHNOLOGIES S A S, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/langendorff perfusion system isolated heart system/product/emka TECHNOLOGIES S A S
Average 90 stars, based on 1 article reviews
langendorff perfusion system isolated heart system - by Bioz Stars, 2026-04
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langendorff perfusion system radnoti working heart system  (Radnoti LLC)
90
Radnoti LLC langendorff perfusion system radnoti working heart system
( A and B ) RBOES was interfaced to the cadaver heart tissue (A) and the potential response under the light stimulation (1 Hz, 100 ms) (B). ( C and D ) RBOES was interfaced to an intercostal nerve (C) and the potential response under the light stimulation (0.5 Hz, 100 ms) (D). The rubbery semiconducting nanofilm side was directly placed on the tissues to form the interface. The potential signals were extracted using a pair of clamp recording electrodes. ( E ) Schematic of the measurement setup including a <t>Langendorff</t> system that maintained the rat hearts. An adult rat heart was placed in an incubator (37°C and 5% CO 2 ), and oxygenated Krebs-Henseleit buffer reservoir was perfused into the aorta of the heart. A 530-nm LED light was focused through an amplifying lens on the RBOES placed onto the exposed myocardium on the right atrium. ECG electrodes were sutured on the heart to record the signals with a data acquisition system. ( F ) Optical images of the perfused rat heart with the RBOES (marked in the dotted square) and the ECG electrodes. ( G ) Real-time beating rate of the perfused rat heart under consecutive stimulation with targeted beating rates of 120 and 150 bpm (marked in the dotted black line). ( H ) ECG signals of the perfused rat heart under optoelectronic stimulation. The top row shows the ECG signals obtained from prestimulation (0 to 5 s), during stimulation (680 to 685 s), and post-stimulation (771 to 776 s) of 2-Hz light illumination. The bottom row shows ECG signals of the perfused rat heart obtained from prestimulation (600 to 605 s), during stimulation (2240 to 2245 s), and post-stimulation (2262 to 2267 s) of 2.5-Hz light illumination. ( I ) Typical ECG with PQRST waves was observed in the signal during stimulation in (H).
Langendorff Perfusion System Radnoti Working Heart System, supplied by Radnoti LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/langendorff perfusion system radnoti working heart system/product/Radnoti LLC
Average 90 stars, based on 1 article reviews
langendorff perfusion system radnoti working heart system - by Bioz Stars, 2026-04
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Image Search Results


( A and B ) RBOES was interfaced to the cadaver heart tissue (A) and the potential response under the light stimulation (1 Hz, 100 ms) (B). ( C and D ) RBOES was interfaced to an intercostal nerve (C) and the potential response under the light stimulation (0.5 Hz, 100 ms) (D). The rubbery semiconducting nanofilm side was directly placed on the tissues to form the interface. The potential signals were extracted using a pair of clamp recording electrodes. ( E ) Schematic of the measurement setup including a Langendorff system that maintained the rat hearts. An adult rat heart was placed in an incubator (37°C and 5% CO 2 ), and oxygenated Krebs-Henseleit buffer reservoir was perfused into the aorta of the heart. A 530-nm LED light was focused through an amplifying lens on the RBOES placed onto the exposed myocardium on the right atrium. ECG electrodes were sutured on the heart to record the signals with a data acquisition system. ( F ) Optical images of the perfused rat heart with the RBOES (marked in the dotted square) and the ECG electrodes. ( G ) Real-time beating rate of the perfused rat heart under consecutive stimulation with targeted beating rates of 120 and 150 bpm (marked in the dotted black line). ( H ) ECG signals of the perfused rat heart under optoelectronic stimulation. The top row shows the ECG signals obtained from prestimulation (0 to 5 s), during stimulation (680 to 685 s), and post-stimulation (771 to 776 s) of 2-Hz light illumination. The bottom row shows ECG signals of the perfused rat heart obtained from prestimulation (600 to 605 s), during stimulation (2240 to 2245 s), and post-stimulation (2262 to 2267 s) of 2.5-Hz light illumination. ( I ) Typical ECG with PQRST waves was observed in the signal during stimulation in (H).

Journal: Science Advances

Article Title: Ultrathin rubbery bio-optoelectronic stimulators for untethered cardiac stimulation

doi: 10.1126/sciadv.adq5061

Figure Lengend Snippet: ( A and B ) RBOES was interfaced to the cadaver heart tissue (A) and the potential response under the light stimulation (1 Hz, 100 ms) (B). ( C and D ) RBOES was interfaced to an intercostal nerve (C) and the potential response under the light stimulation (0.5 Hz, 100 ms) (D). The rubbery semiconducting nanofilm side was directly placed on the tissues to form the interface. The potential signals were extracted using a pair of clamp recording electrodes. ( E ) Schematic of the measurement setup including a Langendorff system that maintained the rat hearts. An adult rat heart was placed in an incubator (37°C and 5% CO 2 ), and oxygenated Krebs-Henseleit buffer reservoir was perfused into the aorta of the heart. A 530-nm LED light was focused through an amplifying lens on the RBOES placed onto the exposed myocardium on the right atrium. ECG electrodes were sutured on the heart to record the signals with a data acquisition system. ( F ) Optical images of the perfused rat heart with the RBOES (marked in the dotted square) and the ECG electrodes. ( G ) Real-time beating rate of the perfused rat heart under consecutive stimulation with targeted beating rates of 120 and 150 bpm (marked in the dotted black line). ( H ) ECG signals of the perfused rat heart under optoelectronic stimulation. The top row shows the ECG signals obtained from prestimulation (0 to 5 s), during stimulation (680 to 685 s), and post-stimulation (771 to 776 s) of 2-Hz light illumination. The bottom row shows ECG signals of the perfused rat heart obtained from prestimulation (600 to 605 s), during stimulation (2240 to 2245 s), and post-stimulation (2262 to 2267 s) of 2.5-Hz light illumination. ( I ) Typical ECG with PQRST waves was observed in the signal during stimulation in (H).

Article Snippet: Cannulated hearts were assembled in the Langendorff perfusion system (Radnoti) and perfused with warm (37°C) oxygenated Krebs-Henseleit buffer (118 mM NaCl, 4.7 mM KCl, 1.2 mM MgSO 4 , 1.25 mM CaCl 2 , 1.2 mM KH 2 PO 4 , 25 mM NaHCO 3 , and 11 mM glucose).

Techniques: